China (Mainland)
**Brinzolamide CAS NO.138890-62-7
- FOB Price: USD: 1.00-1.00 /Gram Get Latest Price
- Min.Order: 10 Gram
- Payment Terms: T/T,MoneyGram,Other
- Available Specifications:
1(1-100)Gram1(1-100)Gram
- Product Details
Keywords
- 138890-62-7
- Brinzolamide
- C12H21N3O5S3
Quick Details
- ProName: **Brinzolamide
- CasNo: 138890-62-7
- Molecular Formula: C12H21N3O5S3
- Appearance: white crystal
- Application: research
- DeliveryTime: 3days
- PackAge: silver bags
- Port: tianjin;shanghai;qingdao
- ProductionCapacity: 20 Metric Ton/Month
- Purity: 99%
- Storage: dry
- Transportation: Mode of Transportation: By air or ship...
- LimitNum: 10 Gram
- Residue on Ignition: 1
- Valid Period: 2040
- state: powder
- cas no: 138890-62-7
Superiority
1.How is the quality
The qualities of most products are above 99% purity,same are 99.5% purity.
2.How is the package
Foil bag or as customer's required.
3.How is the storage
Pls keep dry and cool place.
4.Do I need to pay extra for shipping cost
No,our price includes the shipping cost already,you need not pay for any tax and others.
5.Can I order sample for testing
Of course yes, welcome your sample order before bulk order.We will send the sample directly to your door by express.The quality of sample will prove our ability
6.What is MOQ
Usually our Minimum order quantity is 10g.
Details
Brinzolamide
|
Brinzolamide structure
|
Common Name | Brinzolamide | ||
|---|---|---|---|---|
| CAS Number | 138890-62-7 | Molecular Weight | 383.507 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 586.0±60.0 °C at 760 mmHg | |
| Molecular Formula | C12H21N3O5S3 | Melting Point | N/A | |
| MSDS | ChineseUSA | Flash Point | 308.2±32.9 °C | |
Use of Brinzolamide
Brinzolamide(AL 4862) is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM.Target: carbonic anhydrase IIBrinzolamide (< 1 mg) ophthalmic suspension lowers intraocular pressure in Dutch-belted pigmented rabbits in a dose-dependent manner with an onset within 0.5 hour and a peak response by 1-2 hours. Brinzolamide (0.6 mg) ophthalmic suspension lowers intraocular pressure in laser-treated glaucomatous cynomolgus monkeys in a dose-dependent manner with an onset within 1 hour and a peak response by 3 hours. Brinzolamide dosages of 30 mg/kg, produces a 44% reduction in intestinal charcoal meal progression, but 1 and 10 mg/kg produced 8% and 18% decreases, respectively, in male CD-1 mice. Brinzolamide of 1 mg/kg, 10 mg/kg, and 30 mg/kg prolongs barbiturate sleep time by 57%, 15%, and 35%, respectively, in male CD-1 mice [1]. Brinzolamide (< 3%) produces significantly greater mean percent intraocular pressure reductions and mean intraocular pressure reductions compared with placebo in patients with primary, open-angle glaucoma or ocular hypertension. The optimal intraocular pressure-lowering concentration of brinzolamide is 1%, brinzolamide 1% is well tolerated by patients with primary open-angle glaucoma or ocular hypertension when administered twice daily [2].
